Citi maintains Buy rating on Alnylam shares with steady price target By Investing.com



Citi has reaffirmed its Buy rating and a $342.00 price target for Alnylam Pharmaceuticals (NASDAQ: ALNY).

The endorsement comes after Alnylam’s recent TTR Investor Day, which focused on the challenges and treatment needs associated with transthyretin amyloid cardiomyopathy (ATTR-CM).

The company’s event highlighted the disease’s severity and the growing demand for effective treatments in a competitive market.

Alnylam’s positive momentum is partly due to the encouraging HELIOS-B study results for Amvuttra in treating ATTR-CM, released earlier this year. These findings have positioned Amvuttra to potentially become the first-line, standard care in what is anticipated to be a highly lucrative market.

The firm’s optimism is further supported by Alnylam’s strategic moves, including the submission of a supplemental New Drug Application (sNDA) with a priority review voucher, suggesting a potential FDA decision by April 2025.

The company’s proactive approach is evident as it gears up for a successful product launch, assuming the drug receives approval, which is expected to proceed without an Advisory Committee review. Alnylam has already laid the groundwork for market entry with an established field force, patient support programs, and favorable dynamics with payers.

In other recent news, Alnylam Pharmaceuticals has experienced a series of significant developments. The company’s Q2 earnings report surpassed expectations in revenue and profit, leading to an updated 2024 revenue guidance of between $1.575 billion and $1.65 billion. This financial success is largely attributed to the growth of its TTR franchise and a milestone payment from a licensing agreement with Regeneron (NASDAQ:).

Alnylam also submitted a supplemental New Drug Application (sNDA) to the FDA for vutrisiran, a treatment for ATTR amyloidosis with cardiomyopathy (ATTR-CM), following positive results from the HELIOS-B Phase 3 study. Analyst firms including Goldman Sachs, TD Cowen, BofA Securities, Piper Sandler, and Canaccord Genuity have maintained positive ratings on Alnylam, reflecting these recent developments.

Goldman Sachs reiterated its Buy rating on Alnylam with a price target of $370.00, while BofA Securities maintained a Buy rating with a $307.00 price target. Similarly, Canaccord Genuity maintained a Buy rating with a steady price target of $366.00, and an analyst from TD Cowen also maintained a Buy rating with a price target of $282.00.

Alnylam plans to leverage its experience and existing infrastructure to launch Amvuttra in ATTR-cardiomyopathy. The company also intends to expand its sales force to target an estimated 5,000 cardiologists currently prescribing Vyndamax.

InvestingPro Insights

Alnylam Pharmaceuticals’ (NASDAQ:ALNY) strong market position and growth potential are reflected in recent InvestingPro data. The company’s revenue growth is particularly impressive, with a 107.0% increase in quarterly revenue as of Q2 2024. This aligns with the positive outlook on Amvuttra’s potential in the ATTR-CM market. Additionally, Alnylam boasts a robust gross profit margin of 87.0%, indicating efficient cost management and strong pricing power for its innovative treatments.

InvestingPro Tips highlight that 10 analysts have revised their earnings upwards for the upcoming period, suggesting growing confidence in Alnylam’s financial prospects. This optimism is likely tied to the anticipated success of Amvuttra and the company’s strategic positioning in the ATTR-CM market. Moreover, Alnylam’s stock has shown a strong 77.74% price return over the past six months, reflecting investor enthusiasm about the company’s pipeline and recent clinical successes.

For investors seeking a deeper understanding of Alnylam’s potential, InvestingPro offers 13 additional tips, providing a comprehensive analysis of the company’s financial health and market position.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.





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